The FDA reported in the annual report that CORE 2022 Activities include 65 Incidents Evaluated. Incidents evaluated include potential outbreaks, confirmed outbreaks, and adverse events that the CORE Signals and Surveillance Team evaluated. 28 Responses were initiated, and 11 Advisories were issued. In 2022, CORE investigated four adverse events reported in infant formula, a meal replacement drink, dry cereal, and a frozen food product. These adverse event report investigations rely on self-reported complaints submitted by consumers and health care practitioners and data voluntarily reported by industry to FDA consumer complaint coordinators and the CFSAN Adverse Event Reporting System (CAERS). Noteworthy Outbreaks include (i) Two Enoki mushrooms linked to two recent multistate Listeria outbreaks, one from Korea and the other from China. (ii) Cantaloupe In August 2022, an outbreak of Salmonella Typhimurium infections linked to cantaloupe. Based on traceback information from the 2022 outbreak, FDA conducted investigations in Indiana at three farms, their common packinghouse, and nearby public lands. Salmonella positive environmental samples were found at each location, but none of the resulting Salmonella isolates conclusively matched the outbreak strain by whole genome sequencing (WGS). The outbreak vehicle was confirmed after the outbreak ended. No cantaloupes were recalled, and no public warning was issued as the implicated products were no longer on the market. (iii) Peanut Butter is a multistate outbreak of Salmonella Senftenberg infections linked to certain peanut butter products. Pathogens causing outbreaks: E. coli O157:H7 in packaged salad; Cronobacter in powdered infant formula; Salmonella Senftenberg in peanut butter; Hepatitis A Virus I strawberries; Listeria monocytogenes in ice cream; Listeria monocytogenes in Brie and Camembert; E. coli O121 in frozen falafel; Salmonella Litchfield in seafood; Listeria monocytogenes in Enoki Mushrooms; and Salmonella Typhimurium in sprouts. @ https://www.fda.gov/media/175176/download?attachment
