Scientists may have new weapon to fight Listeria

Researchers from North Carolina State University have identified new compounds that may be effective in restraining the virulence of Listeria. Researchers at the university knew that inhibiting glucose-1-phosphate uridylyltransferase (GalU) — led to dramatic modifications of the bacterial cell surface. These chemical modifications, in turn, rendered Listeria much less virulent and less able to cause illness. Computer models found 37 compounds promising enough to be tested in vitro, three of which were deemed effective enough to warrant further study. Their study shows that small molecules can be developed to shut down the activity of a specific bacterial enzyme, leading to the suppression of virulence. @ http://www.foodsafetynews.com/2018/03/researchers-may-have-found-new-way-to-fight-drug-resistant-bacteria/#.WqlH5ujwaM8