A study was published in Communications Biology (Delgado-Blas, J.F., Ovejero, C.M., David, S. et al. Population genomics and antimicrobial resistance dynamics of Escherichia coli in wastewater and river environments. Commun Biol 4, 457 (2021)) with the goal to understand the population genomics and evolutionary events of Escherichia coli resistant to clinically important in natural water ecosystems. The study shows that less different E. coli sequence types (STs) are identified in wastewater than in rivers. However, more resistant to antibiotics and significantly more plasmids/cell (6.36 vs. 3.72) is seen in rivers. The genomic diversity within E. coli STs in both aquatic environments is similar. Wastewater environments favor the selection of conserved chromosomal structures associated with diverse, flexible plasmids, unraveling promiscuous interplasmidic resistance genes flux. @ https://www.nature.com/articles/s42003-021-01949-x
Antimicrobial resistance of Escherichia coli in wastewater and river environments
Jose F. Delgado-Blas et al. report a genomic analysis of two antimicrobial-resistant E. coli populations from wastewater and river water. They find that bacteria from wastewater are more resistant to antibiotics and rely on a diverse set of plasmids for adaptation, while river bacteria adapt mainly via chromosomal changes.