A New compound which killed antibiotic resistant gram-negative bacteria was discovered

A team from the University of Sheffield's Department of Chemistry, led by Professor Jim Thomas, is testing new compounds developed by his Ph.D. student Kirsty Smitten on antibiotic-resistant gram-negative bacteria, including pathogenic E. coli. Gram-negative bacteria are difficult to treat because their cell wall prevents drugs from getting into the cell. New treatments for gram-negative bacteria are imperative as g- bacteria are rapidly becoming immune to current drugs. The new drug compound has a range of exciting opportunities. Professor Jim Thomas explains: "As the compound is luminescent it glows when exposed to light. This means the uptake and effect on bacteria can be followed by advanced microscopy techniques. The research, published in the journal ACS Nano. @ https://www.eurekalert.org/pub_releases/2019-05/uos-nc052219.php